I take 200mg of oral progesterone as transfemme hormone therapy, I've been on it for a while and I and a good number of other transfemmes I know have experimented with taking high doses of it recreationally.
The claim that progesterone doesn't have any side effects at the doses you're talking about is very contrary to a lot of testimonials as well as pharmacological effects that should be kind of obvious. The metabolite you're trying to maximize here is a a GABA-A receptor agonist, which is going to give it somewhat intoxicating, sedative effects heading towards nauseating and disorienting as dosage trends upwards. It can also significantly spike your libido. These aren't totally bad effects and they might even be a part of what you want for treating PPD, but saying "there's no side effects" is just not true.
There's also multiple kinds of progresterone on the market and non-bioidentical progesterone is much worse than bioidentical, when I was on it for a month it made me suicidally depressed, taking a high dose of that might be legitimately dangerous to someone's mental health.
I take 200mg of oral progesterone as transfemme hormone therapy, I've been on it for a while and I and a good number of other transfemmes I know have experimented with taking high doses of it recreationally.
The claim that progesterone doesn't have any side effects at the doses you're talking about is very contrary to a lot of testimonials as well as pharmacological effects that should be kind of obvious. The metabolite you're trying to maximize here is a a GABA-A receptor agonist, which is going to give it somewhat intoxicating, sedative effects heading towards nauseating and disorienting as dosage trends upwards. It can also significantly spike your libido. These aren't totally bad effects and they might even be a part of what you want for treating PPD, but saying "there's no side effects" is just not true.
There's also multiple kinds of progresterone on the market and non-bioidentical progesterone is much worse than bioidentical, when I was on it for a month it made me suicidally depressed, taking a high dose of that might be legitimately dangerous to someone's mental health.