For what it's worth: my spouse has been prescribed supplemental progesterone to treat infertility, and the side effects were pretty bad - her doctor had her cut back her dose. She would have had to be *very* depressed to make the enduring the side effects worth it.
The major effect was sleep-disturbance-via-anxiety: she would wake up in a panic, confused about her surroundings, sometimes screaming for help. Then she wouldn't be able to sleep the rest of the night.
(she did not have any side effect like this when pregnant)
For what it's worth: my spouse has been prescribed supplemental progesterone to treat infertility, and the side effects were pretty bad - her doctor had her cut back her dose. She would have had to be *very* depressed to make the enduring the side effects worth it.
The major effect was sleep-disturbance-via-anxiety: she would wake up in a panic, confused about her surroundings, sometimes screaming for help. Then she wouldn't be able to sleep the rest of the night.
(she did not have any side effect like this when pregnant)