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Jun 12, 2021Liked by Byrne Hobart

In defense of Katerra, construction costs make up most of the price in markets where you can build. The markets where you can’t build - well, you can’t build there anyway, at least not yet ;) But there are enough places around the world where you can to work out the kinks on a new way of building, I think.

Re business travel, in person is so high bandwidth relative to any alternative that you would expect any very high value collaboration to still happen in person, such as M&A. Historically new developments in communications tech have been complements to business travel - Ed Glaeser has pointed out that there is sort of a Jevons paradox, it increases the demand for collaboration, the internet now lets us bring together 10 people in different countries to build software and then you realize it’s most efficient to relocate them all to the same city or have them travel to meet each other, depending on the expected economics and their preferences. Not sure if video is quite comparable to the printing press, phone or internet in that it doesn’t represent the same leap in being able to connect people and share ideas, but it might sort out that way with business travel- it’s really expensive to put everyone in the same city and some people hate big cities or are blocked by immigration restrictions so the next best solution is a combo of video, email, and travel.

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Please feel free to delete this if it's not allowed, but I'd love to talk to any Diff readers who are interested in drug development, from either an academic or practical perspective.

I'm the president of a preclinical pharmaceuticals company working on autoimmune diseases, and trying to further my own thinking around the practicalities of drug development. Feel free to comment below if you're interested, or reach out through highwaypharm.com .

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